PRP for Infertility Support

 

Twelve percent of women of childbearing age in the

have difficulty getting or staying pregnant.

With more women delaying childbirth until

later in life, ovarian insufficiency has become

a rising problem. Infertility can present emotional,

mental, and financial challenges both for the

patient and her partner.

 

The challenge for the physician is helping the patient find safe and effective treatment options with minimal invasiveness and side effects.

The current options for achieving fertility in women with ovarian insufficiency include:

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• Synthetic hormone treatment

• In vitro fertilization using donor eggs

 

However, many women aren’t comfortable with the side effects of hormone treatment which include increased risk of cardiovascular disease and breast cancer. Many women are also unable to afford the expense of in vitro fertilization or are uncomfortable with the necessity of using donor eggs.

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Ovarian rejuvenation through platelet-rich plasma (PRP) is showing promise as a safe and effective therapy to support fertility.

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Regenerative Medicine in Fertility Treatments Webinar

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• Dr. Stephan Gordts - Gynaecologist - Life Expert Center

• Dr. Rudi Campo - Fertility expert - Life Expert Center

• Sonia Herraiz, PH.D. - Ovarian Rejuvenation and Fertility Preservation

• Lucía De Miguel Gómez, PD.D. Student - at IVI RMA GLOBAL

• Dr. Anita Van Domselaar - Co-Founder Benorm, Regenerative Medicine Specialist, Certified Interventional Pain Sonologist, Anesthetist, Life Expert Center

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Platelet-Rich Plasma to Treat Infertility

 

Platelet-rich plasma, or PRP, is gaining traction as an alternative treatment option for infertility. PRP may use the body’s own natural healing process to help regenerate damaged ovarian tissue.

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But how does it work? PRP stimulates the body’s innate healing cascade. When we experience an injury, our body responds by delivering a rush of platelet cells. When these platelets are activated, they release several types of growth factors, proteins, and cytokines that play a fundamental role in cell regeneration and tissue healing.

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But PRP takes the natural healing response one step further by separating platelets from other blood components and concentrating them. This specially prepared platelet-rich plasma contains 5 to 10 times the concentration of platelets found in whole blood. The concentrated PRP is then delivered into the ovaries via injection using an ultrasound-guided or laparoscopic-assisted approach. The delivery of the concentrated platelet-rich plasma stimulates and significantly strengthens the body’s healing response within the ovaries.

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Intraovarian PRP injection has been shown to aid a menopausal woman in becoming pregnant.6 Ovarian PRP treatment also may have helped restore menstruation in three women who hadn’t had a menstrual cycle in over a year. These women also achieved pregnancy via natural conception within a year after PRP treatment. The women also showed:

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• Improved hormonal profile

• Decreased follicle-stimulating hormone (FSH) levels

• Increased anti-Müllerian hormone (AMH) levels

 

Since PRP is an autologous therapy, using the patient’s own blood product, there is no risk of cross reactivity or immune reaction.

 

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